PCOS valla periods irregularly vastunnaya? Garbham raakupodutundaa? Mother Hospitals lo Dr. E. Prashanthi Reddy tho complete PCOS chikitsa — lifestyle to IVF varaku.
19+ Years Experience · PCOS Specialist · IVF Centre · Boduppal, Hyderabad
PCOS (Polycystic Ovary Syndrome) causes irregular periods and prevents ovulation — making pregnancy difficult. But it is one of the most treatable causes of infertility. At Mother Hospitals Boduppal, treatment starts simple: lifestyle changes and letrozole tablets restore ovulation in most women. If that's not enough, IUI or IVF is the next step. Call 97059 93366 for a PCOS consultation today.
PCOS presents differently in different women — identifying your type guides the right treatment
Most common type (70%). Weight gain especially around the abdomen, dark patches on neck (acanthosis nigricans), strong sugar cravings, fatigue after meals. High fasting insulin. Responds well to metformin + low-carb diet.
Most CommonNormal BMI but PCOS symptoms — irregular periods, high androgens, polycystic ovaries on scan. Often caused by adrenal androgen excess or post-pill hormonal disruption. Metformin may be less effective; letrozole and stress management are key.
Normal WeightChronic low-grade inflammation drives androgen production. Associated with fatigue, headaches, joint pain, and skin problems beyond acne. Anti-inflammatory diet (omega-3, turmeric, avoid gluten) alongside hormonal treatment gives best results.
Inflammation-DrivenPeriods were regular on the contraceptive pill, but stopped or became irregular after stopping it. The pill was masking underlying PCOS. Usually resolves within 3–6 months with hormonal support, but may need ovulation induction if trying to conceive.
Pill-InducedPCOS affects multiple systems — it's not just a period problem
Cycles longer than 35 days, fewer than 8 periods per year, or absent periods. The most common presenting complaint.
Tenglish: Periods irregularly vadam, nela skip avvadam
No ovulation = no egg = no pregnancy. PCOS is the cause in nearly half of women investigated for infertility at Mother Hospitals.
Tenglish: Garbham raakupodadam, PCOS valla vandhatvam
Unexplained weight gain, especially around the waist. Difficulty losing weight despite diet and exercise — driven by insulin resistance.
Tenglish: Baduvuna peragadam, belly fat thaggadam kashtam
Unwanted hair growth on the face (upper lip, chin), chest, stomach, or inner thighs — driven by elevated testosterone.
Tenglish: Face meeda undesired hair growth, hirsutism
Hormonal acne — jaw line, chin, cheeks. Does not fully respond to typical skin treatments alone. Improves with anti-androgen therapy.
Tenglish: Hormone valla face meeda pimples, acne
Scalp hair thinning, especially at the crown or temples — androgenic alopecia driven by DHT. Worsens with age if PCOS is untreated.
Tenglish: Nuti vudadam, scalp hair thinning PCOS valla
Darkened velvety skin at the nape of the neck, underarms, or groin — acanthosis nigricans. A strong sign of insulin resistance.
Tenglish: Meeda charmam nalupaga avvadam, neck meeda dark patches
Persistent tiredness, difficulty concentrating, anxiety, and depression are common in PCOS — linked to insulin dysregulation and hormonal imbalance.
Tenglish: Akkarana leka ayyaram anipinchadu, mood swings
Rotterdam Criteria — 2 of 3 must be present for a confirmed PCOS diagnosis
LH:FSH ratio (elevated in PCOS), total and free testosterone, DHEAS (adrenal androgens), prolactin (to rule out other causes), thyroid (TSH), fasting insulin and glucose (insulin resistance), AMH (typically elevated in PCOS — confirms polycystic pattern).
Counts antral follicles (≥12 per ovary = polycystic morphology) and measures ovarian volume (>10 mL). Also checks for dominant follicle (confirms anovulation if absent mid-cycle) and uterine lining. First-line investigation at Mother Hospitals.
Detailed menstrual history — cycle length, regularity, duration. Clinical signs of androgen excess: hirsutism score (Ferriman-Gallwey), acne severity, scalp hair loss pattern. BMI, waist circumference, blood pressure, and skin examination for acanthosis nigricans.
For couples trying to conceive, a semen analysis is done simultaneously — male factor infertility is present in 40% of couples with PCOS. Treating PCOS alone may not be sufficient if sperm quality is also reduced. A joint plan covers both partners.
Always start with the simplest effective option — escalate only if needed
5–10% weight loss restores ovulation in 55–70% of overweight PCOS women. Metformin improves insulin sensitivity, regularises periods, and lowers androgens. 3–6 months trial.
Ovulation induction tablets taken on Day 2–6 of the cycle. Letrozole (preferred) achieves ovulation in 70–80% of PCOS women and pregnancy in 40–50% within 6 cycles.
Low-dose FSH injections trigger controlled ovarian stimulation. IUI places washed sperm directly into the uterus at ovulation. 3–4 cycles before moving to IVF.
Controlled stimulation retrieves multiple eggs. All embryos are frozen to avoid OHSS risk. Transfer in a subsequent calmer FET cycle — highest pregnancy rates.
For older women or those with additional male factor. ICSI maximises fertilisation. PGT-A screens embryos for chromosomal normality before transfer — best success rate.
PCOS patients respond strongly to stimulation — a specialised protocol prevents OHSS while maximising success
Metformin 2–3 months before IVF reduces OHSS risk and improves egg quality. Vitamin D, myo-inositol, and antioxidants support follicle health in insulin-resistant PCOS.
PCOS-specific: inositol supplementation shown to improve oocyte quality
Starting with low FSH doses (75–100 IU) minimises OHSS risk. Daily monitoring with ultrasound and oestradiol levels — dose adjusted every 2–3 days.
PCOS-specific: "step-up" or "low and slow" protocol to avoid hyper-response
Instead of hCG trigger, a GnRH agonist (Lupron) triggers final egg maturation in PCOS — nearly eliminates severe OHSS risk while preserving good egg maturity.
PCOS-specific: GnRH agonist trigger is standard of care in PCOS IVF
PCOS patients often retrieve 15–25 eggs in one cycle (high responders). Even with lower fertilisation rates, more eggs means more embryos to work with.
PCOS advantage: abundant eggs — more chances per cycle
All good embryos are vitrified (frozen) — NO fresh transfer. This allows OHSS to fully resolve before implantation. Frozen embryo transfer (FET) gives 20–30% better implantation in PCOS.
PCOS-specific: freeze-all is standard practice — not a compromise
1–2 months after retrieval. Uterus prepared with oestrogen and progesterone. 1–2 embryos transferred. Pregnancy test 12–14 days later. PCOS women have excellent implantation rates in FET cycles.
PCOS advantage: endometrial receptivity is often better in FET cycles
Dr. E. Prashanthi Reddy answers the most common PCOS questions
Yes — PCOS is one of the most treatable causes of infertility. Because the core issue is anovulation, simply restoring ovulation through lifestyle changes, metformin, or letrozole tablets is enough for many women to conceive naturally. For those who need more support, IUI or IVF has excellent success rates in PCOS. Dr. Prashanthi at Mother Hospitals uses a step-up approach — starting with the simplest, most effective intervention first.
Avunu — PCOS valla infertility chala common, kaani idi treat cheyyadam chala easy. Letrozole tablets tho ovulation restore cheyyadam, metformin tho insulin resistance treat cheyyadam — ivi chaduru ga pani chestai. Ivi pani cheyyakapothe IUI leda IVF next steps. Mother Hospitals lo 80% PCOS patients ki successful pregnancy vasthundi treatment tho.
PCOS (Polycystic Ovary Syndrome) and PCOD (Polycystic Ovarian Disease) are often used interchangeably. PCOD refers specifically to the ultrasound finding of polycystic ovaries — many small follicles. PCOS is the full syndrome including irregular periods, hormonal imbalance, and androgen excess. You can have polycystic ovaries on scan without having the syndrome. Both terms refer to the same condition in everyday clinical practice in India.
Yes — significantly. Losing just 5–10% of body weight can restore regular ovulation, reduce androgen levels, improve insulin sensitivity, and regularise periods — sometimes without any medication at all. This is particularly true for insulin-resistant PCOS (the most common type). For lean PCOS (normal BMI), weight loss is less central and the focus shifts to hormonal treatment and stress management.
Letrozole (an aromatase inhibitor) is the first-line ovulation induction medication for PCOS — preferred over clomiphene because it has fewer anti-oestrogenic effects on the uterine lining. It is taken on Days 2–6 of the cycle and achieves ovulation in 70–80% of PCOS patients. Metformin is added for insulin-resistant PCOS. If 3–6 letrozole cycles fail, FSH injections with IUI are next, followed by IVF.
IVF is very effective for PCOS but PCOS patients carry a higher risk of Ovarian Hyperstimulation Syndrome (OHSS) — where the ovaries over-respond to stimulation drugs, becoming enlarged and leaking fluid into the abdomen. Mild OHSS is manageable; severe OHSS can be dangerous. At Mother Hospitals, we use a 'freeze-all' strategy for PCOS — all embryos are frozen and transferred in a later, safer cycle — nearly eliminating severe OHSS while maintaining excellent success rates.
Not necessarily. Irregular periods can also be caused by thyroid problems (hypothyroidism is very common in Indian women), elevated prolactin (hyperprolactinaemia), premature ovarian insufficiency (early menopause), extreme weight loss, excessive exercise, or stress. A proper PCOS diagnosis requires meeting 2 of 3 Rotterdam criteria — irregular periods alone is not enough. A complete workup at Mother Hospitals will identify the exact cause.
In PCOS, AMH is typically elevated (3–10 ng/mL vs. normal 1–3 ng/mL) because of the large number of small antral follicles in the polycystic ovaries. High AMH in PCOS confirms the diagnosis but does NOT mean better egg quality — it signals high OHSS risk in IVF. For IVF stimulation, high AMH PCOS patients need very careful, low-dose protocols. Dr. Prashanthi calibrates your IVF stimulation specifically to your AMH to maximise safety and success.
PCOS is a lifelong hormonal condition and cannot be permanently cured. However, it is very well managed: lifestyle changes address the insulin resistance, medications regulate the hormonal imbalance, and fertility treatments restore ovulation for conception. Many women with PCOS lead completely normal lives and have successful pregnancies. After completing their family, the combined oral contraceptive pill is commonly used to protect the uterine lining from the effects of prolonged irregular cycles.
At Mother Hospitals: consultation and initial PCOS workup (blood tests + TVS) starts at ₹1,500–3,000. Letrozole ovulation induction cycles cost ₹3,000–6,000 per cycle including monitoring scans. IUI for PCOS is ₹15,000–20,000 per cycle. IVF all-inclusive is ₹99,000. Contact us at 97059 93366 for a personalised cost estimate based on your specific PCOS workup results.
Mother Hospitals, Boduppal — Dr. E. Prashanthi Reddy — 19+ samvatsarala anubhavam gala fertility nipunuralu
PCOS (Polycystic Ovary Syndrome) lo ovaries meeda chala small follicles erpadata. Hormone imbalance valla periods irregularly vastayi, ovulation avvadu, weight perigipotundi. 5 lo 1 stree ki PCOS untundi — kaani idi treat cheyyadam possible.
PCOS patients ki IVF lo chala eggs vasatayi — idi advantage. Kaani OHSS risk untundi — akkarana Mother Hospitals lo "freeze-all" strategy use chestam. Anni embryos freeze chestam, tarvata safer FET cycle lo transfer chestam. PCOS ki idi best approach.
PCOS valla periods problem leda garbham raakupodutundaa? Ippudey sampradinchandi.
📞 97059 93366 ki call cheyandi 💬 WhatsApp lo matladandiComplete fertility care under one roof