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Male Infertility Treatment in Hyderabad

Male factor is present in 40–50% of infertility cases. At Mother Hospitals, we provide complete male infertility evaluation and treatment — from semen analysis and sperm DNA testing to TESA, PESA, and ICSI — helping couples conceive even with severely compromised male factor.

Dr. E. Prashanthi Reddy – Male Infertility Treatment Hyderabad

Dr. E. Prashanthi Reddy

MBBS, DGO, PG Diploma in ART – Kiel University, Germany | Male Factor & IVF Specialist | TGMC Reg: 50624

Male Infertility — Evaluation at Mother Hospitals

🔬 Semen Analysis (SA)

The first and most important test. Evaluates sperm count, motility (movement), and morphology (shape). WHO 2021 reference values: count >16 million/mL, motility >42%, normal morphology >4%. Results available same day.

🧬 Sperm DNA Fragmentation (DFI)

Measures percentage of sperm with damaged DNA. High DFI (>25%) associated with failed IVF, poor embryo quality, and recurrent miscarriage. Critical test for unexplained infertility and repeated IVF failure.

🩸 Hormone Profile

FSH, LH, testosterone, prolactin — identifies hormonal causes of male infertility including hypogonadism, pituitary issues, and hyperprolactinaemia. Some hormonal causes are treatable with medication to restore sperm production.

🧫 Azoospermia Evaluation

No sperm in semen is called azoospermia. Evaluation includes FSH, testicular size, and genetic testing (karyotype, Y-chromosome microdeletion). Distinguishes obstructive (blockage) from non-obstructive (production failure) — each has different treatment.

🧬 Genetic Testing

Karyotype (for Klinefelter syndrome 47,XXY) and Y-chromosome microdeletion analysis — recommended for severe oligospermia (<5 million) or azoospermia. Important before TESA to predict success and counsel on genetic risks to offspring.

🔍 Scrotal Ultrasound

Detects varicocele (dilated testicular veins — most common treatable cause of male infertility), epididymal cysts, testicular atrophy. Varicocele repair can significantly improve sperm parameters.

Male Infertility Treatment — Available Options

1

Lifestyle & Antioxidant Therapy

For mild oligospermia: quit smoking, reduce alcohol, maintain healthy weight, avoid heat (laptops, hot baths). Antioxidant supplements (CoQ10, zinc, folic acid, lycopene) for 3 months improve sperm parameters significantly in mild cases.

2

Hormonal Treatment

For hypogonadism or hyperprolactinaemia: gonadotropin injections (FSH/hCG) can restore sperm production over 3–6 months. Success depends on the underlying cause and testicular function.

3

IUI with Processed Sperm

For mild male factor (count >5 million/mL, reasonable motility): sperm washing and density gradient processing concentrates the best sperm for intrauterine insemination (IUI), improving conception chances.

4

ICSI (Intracytoplasmic Sperm Injection)

For moderate-severe male factor: a single healthy sperm is injected directly into each egg. Even with very low counts (1–2 million/mL), ICSI achieves fertilisation rates of 70–80%. All IVF at Mother Hospitals includes ICSI.

5

TESA / PESA for Azoospermia

When no sperm appears in semen: PESA retrieves sperm from the epididymis; TESA retrieves from testicular tissue. Retrieved sperm is used for ICSI. Success rate depends on whether azoospermia is obstructive (higher) or non-obstructive (lower but possible).

Frequently Asked Questions — Male Infertility

Is male infertility common?

Yes. Male factor is present in 40–50% of all infertile couples. In 20–30% of cases, male factor is the sole cause. It is as common as female factor infertility. Both partners should be evaluated simultaneously — not sequentially — to avoid delays in treatment.

Can a man with zero sperm count (azoospermia) have a biological child?

Often yes. For obstructive azoospermia (blockage), TESA/PESA successfully retrieves sperm in nearly all cases. For non-obstructive azoospermia (testicular failure), TESA retrieves sperm in 30–50% of cases. The retrieved sperm is used for ICSI to fertilise the partner's eggs.

What is the cost of TESA at Mother Hospitals?

TESA/PESA cost is discussed during consultation and is separate from the ₹99,000 IVF package. It is a day procedure performed under local anaesthesia. The retrieved sperm is immediately used for ICSI within the same IVF cycle or frozen for later use.

Can high sperm DNA fragmentation be treated?

Yes. Antioxidant therapy (CoQ10, vitamin E, zinc, lycopene) for 3 months can significantly reduce DFI. Varicocele repair (if present) also improves DFI. In IVF, PICSI (physiological ICSI) selects sperm with lowest DNA damage for injection, improving embryo quality.

Does the wife need IVF if the husband has low sperm count?

Not always. For mild male factor (count >5 million, reasonable motility), IUI with processed sperm is the first option. For moderate-severe male factor, ICSI as part of an IVF cycle is recommended. The decision depends on both partners' fertility assessments combined.

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