Male factor infertility accounts for 40–50% of all infertility cases. At Mother Hospitals & IVF Center, Boduppal, Hyderabad, Dr. E. Prashanthi Reddy (MBBS, DGO, TGMC-50624) treats all forms of male infertility — low sperm count, azoospermia, poor motility, abnormal morphology, and high DNA fragmentation — using ICSI, TESA/PESA, and personalised IVF protocols. All-inclusive IVF+ICSI package: ₹99,000. OPD: 10:30 AM–1:30 PM, all days. Call 97059 93366 | WhatsApp.
Low sperm count, azoospermia, poor motility, DNA fragmentation — expert male fertility care with ICSI and TESA at Mother Hospitals & IVF Center, Boduppal, Hyderabad.
Male infertility has many causes — most are treatable with the right diagnosis. A simple semen analysis is the first step. Further testing identifies the underlying cause.
Sperm count below 16 million/mL. Causes include varicocele, hormonal imbalance, heat exposure, lifestyle factors, and genetic conditions. Treated with ICSI — even a handful of sperm is enough.
Complete absence of sperm in ejaculate. Obstructive type — blocked ducts, sperm production normal — treated with TESA/PESA + ICSI. Non-obstructive — production failure — micro-TESA may retrieve sperm in selected cases.
Total motility below 42% or progressive motility below 30%. Sperm cannot swim to the egg. ICSI bypasses this by injecting sperm directly into the egg, eliminating the need for motility.
Normal morphology below 4% (Kruger strict). Abnormally shaped sperm struggle to penetrate the egg membrane. ICSI selects the best-shaped sperm for injection, overcoming poor morphology.
DNA damage inside sperm — invisible on routine semen analysis but causes poor embryo quality and recurrent miscarriage. Detected by specialised DFI testing. Treated with antioxidants, PICSI, or testicular sperm retrieval.
Low testosterone, elevated FSH, or high prolactin can suppress sperm production. Hormonal panel identifies the cause. Treated with targeted hormonal therapy before or during IVF.
Dilated veins in the scrotum raise testicular temperature, damaging sperm production. Present in 35–40% of infertile men. Varicocelectomy (surgical repair) can significantly improve sperm parameters.
Y-chromosome microdeletion (causes azoospermia/severe oligospermia) and Klinefelter's syndrome (47,XXY — causes azoospermia) are genetic causes. Karyotyping and Y-deletion testing identify these.
WHO 2021 reference values — what your semen analysis report means:
| Parameter | Normal (WHO 2021) | Below Normal | Treatment |
|---|---|---|---|
| Sperm count | ≥16 million/mL | <16 million = oligospermia | ICSI |
| Total motility | ≥42% | <42% = asthenospermia | ICSI |
| Progressive motility | ≥30% | <30% | ICSI |
| Morphology | ≥4% normal (Kruger) | <4% = teratospermia | ICSI |
| DNA fragmentation | <15% DFI | >30% DFI = high | PICSI / antioxidants / TESA |
| Sperm in ejaculate | Sperm present | None = azoospermia | TESA/PESA + ICSI |
Note: Below-normal parameters do not mean IVF cannot work. ICSI achieves fertilisation even with severely reduced parameters. Consult Dr. Prashanthi Reddy for your personalised assessment.
Semen analysis (WHO 2021 criteria) · Sperm DNA fragmentation index (DFI) · Hormonal panel (FSH, LH, testosterone, prolactin) · Scrotal ultrasound · Karyotyping if indicated · Y-chromosome microdeletion testing for azoospermia
Quit smoking · Reduce alcohol · Avoid scrotal heat (hot baths, laptops on lap, tight underwear) · Antioxidant supplements: CoQ10, Vitamin C & E, Zinc, Selenium, Folic acid · Healthy weight · Treat underlying conditions (varicocele, infection)
The gold-standard treatment for all forms of male factor infertility. A single sperm is injected directly into each mature egg. Fertilisation rate: 60–80% per egg. Included in the Mother Hospitals ₹99,000 all-inclusive IVF package. Even a handful of abnormal sperm can achieve fertilisation with ICSI.
For azoospermia, sperm is retrieved directly from the testis (TESA) or epididymis (PESA) under local anaesthesia. Retrieved sperm is used immediately for ICSI or cryopreserved. Obstructive azoospermia has excellent outcomes. Non-obstructive cases depend on finding viable sperm in testicular tissue.
Physiological ICSI (PICSI) selects sperm with intact DNA by testing sperm binding to hyaluronic acid (a natural sperm selection mechanism). Recommended when DFI >30% — improves embryo quality and reduces miscarriage risk compared to conventional ICSI.
All-inclusive package: ₹99,000 (valid till 30 June 2026). TESA/PESA quoted separately. Call 97059 93366 for details.
The most common causes are low sperm count (oligospermia), poor motility (asthenospermia), and abnormal morphology (teratospermia). Varicocele (dilated scrotal veins) is the most common correctable cause, found in 35–40% of infertile men. All are treatable with ICSI at Mother Hospitals. Read: male infertility treatment guide.
Yes — in many cases. Obstructive azoospermia (blocked ducts, sperm production intact) is treated with TESA/PESA to retrieve sperm for ICSI. Outcomes are excellent. Non-obstructive azoospermia (production failure) may still yield sperm with micro-TESA in selected cases. Many azoospermic men have fathered children through ICSI at Mother Hospitals. Consult Dr. Prashanthi Reddy for your specific case. See: TESA and PESA explained.
DNA Fragmentation Index (DFI) measures sperm with damaged DNA. Normal: <15%. High DFI (>30%) causes poor embryo quality, fertilisation failure, and recurrent miscarriage — even when routine semen analysis looks normal. Treatment: antioxidant therapy, PICSI (physiological sperm selection), or testicular sperm retrieval (testicular sperm has significantly less DNA damage than ejaculated sperm). See: DFI in fertility glossary.
Yes — sperm regenerates every 72–90 days, so improvements appear in semen analysis after 3 months. Key changes: quit smoking (most impactful), reduce alcohol, avoid scrotal heat, exercise regularly, maintain healthy weight, take antioxidants (CoQ10, Zinc, Vitamin C & E). Avoid anabolic steroids — they completely suppress sperm production and may cause irreversible damage.
Yes — ideally both partners attend the initial consultation. The husband provides a semen sample on the day of egg retrieval (OPU). For TESA/PESA, a pre-operative consultation is required. For the monitoring phase (ultrasound scans during stimulation) only the wife needs to attend. Remote couples receive telemedicine coordination support.
Avunu — sperm count takkuva unte kuda ICSI technique tho baby possible. Oka sperm matrame provide chestunte ICSI tho egg fertilise avutundi. Mother Hospitals lo Dr. Prashanthi Reddy highly experienced in ICSI treatment. Call: 97059 93366.